24
76
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T27951 |
LY392098
LY-392098,LY 392098,AMPA receptor modulator-3 |
GluR; iGluR | Membrane transporter/Ion channel; Neuroscience |
LY392098 (AMPA receptor modulator-3) 是 AMPA 受体的变构调节剂,EC50 为 4.4 μM,可用于哺乳动物神经系统的研究。 | |||
T1755 |
LY2090314
|
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
LY2090314 是GSK-3抑制剂,抑制 GSK-3α (IC50:1.5 nM) 和 GSK-3β (IC50:0.9 nM)。 | |||
T8875 |
CD73-IN-3
EX-A4254,LY-3475070 |
CD73 | Immunology/Inflammation |
CD73-IN-3 (LY-3475070) 是一种有效的选择性 CD73 抑制剂,IC50 为 28 nM,具有癌症的研究潜力。 | |||
T11905 |
LY-411575 isomer 3
|
Others | Others |
LY-411575 isomer 3 is a potent γ-secretase inhibitor. LY-411575 isomer 3 is an isomer of LY411575. | |||
T4079 |
LY-294002 hydrochloride
SF 1101,LY 294002,NSC 697286 |
PI3K | PI3K/Akt/mTOR signaling |
LY-294002 hydrochloride (NSC 697286) 是一种合成的 PI3Kα/δ/β 分子抑制剂(IC50:0.5/0.57/0.97 μM,在无细胞试验中);在溶液中比 Wortmannin 更稳定,也是自噬体形成的阻断剂。 | |||
T3455 |
Merestinib
LY2801653 |
Discoidin Domain Receptor (DDR); FLT; c-Met/HGFR; ROS; ROS Kinase | Angiogenesis; Immunology/Inflammation; Tyrosine Kinase/Adaptors |
Merestinib (LY2801653) 是一种有效的口服生物可利用的具有抗肿瘤活性的c-Met 抑制剂。 | |||
T4266 |
LY334370
4-氟-N-(3-(1-甲基哌啶-4-基)-1H-吲哚-5-基)苯甲酰胺盐酸盐,LY 334370 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
LY334370 是一种选择性5-HT1F 受体激动剂,Ki 值为 1.6 nM。 | |||
T6883 |
Samotolisib
GTPL8918,LY3023414 |
DNA-PK; PI3K; mTOR; Autophagy | Autophagy; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling |
Samotolisib (LY3023414) 在低纳摩尔浓度下,有效抑制mTORC1/2。它选择性地有效抑制PI3Kα、PI3Kβ、PI3Kδ、PI3Kγ、DNA-PK 和mTOR,IC50分别为 6.07 nM、77.6 nM、38 nM、23.8 nM、4.24 nM 和 165 nM。它可用于多种肿瘤和癌症的试验。 | |||
T2638 |
Gandotinib
LY2784544 |
VEGFR; FGFR; FLT; JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors |
Gandotinib (LY2784544) 是一种JAK2抑制剂,IC50为 3 nM。它也抑制FLT3、FLT4、FGFR2、TYK2 和 TRKB,IC50分别为 4、25、32、44 和 95 nM。 | |||
T78097L |
Mazdutide acetate(2259884-03-0 free base)
Mazdutide acetate(2259884-03-0 free base),OXM-3 acetate,LY-3305677 acetate,IBI-362 acetate |
Glucagon Receptor | GPCR/G Protein |
Mazdutide acetate 是一种高效的胰高血糖素样肽 (GLP-1R) 与胰高血糖素受体 (GCGR) 的共激动剂,是一种胃泌酸调节素类似物。Mazdutide acetate可刺激小鼠胰岛的胰岛素分泌 ,可用于研究肥胖和 2 型糖尿病 (T2D) 。 | |||
T9078 |
LY3405105
1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester |
CDK | Cell Cycle/Checkpoint |
LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester) 是一种新型 CDK7 抑制剂。 | |||
T4310 |
Prexasertib
5-[[5-[2-(3-氨基丙氧基)-6-甲氧基苯基]-1H-吡唑-3-基]氨基]-2-吡嗪甲腈,LY2606368 |
Apoptosis; Chk | Apoptosis; Cell Cycle/Checkpoint |
Prexasertib (LY2606368) 是一种具有潜在抗肿瘤活性的检查点激酶 1 抑制剂。它可引起双链 DNA 断裂和复制突变,导致细胞凋亡。 | |||
T2008 |
LY294002
LY 294002,NSC 697286,SF 1101 |
Apoptosis; DNA-PK; Casein Kinase; PI3K; Autophagy | Apoptosis; Autophagy; DNA Damage/DNA Repair; Metabolism; PI3K/Akt/mTOR signaling; Stem Cells |
LY294002 (SF 1101) 是一种 PI3K 的广谱抑制剂,抑制 PI3Kα、PI3Kδ 和 PI3Kβ (IC50=0.5/0.57/0.97 μM)。LY294002 也是 DNA-PK 抑制剂 (IC50=1.4 μM) 和 CK2 抑制剂 (IC50=98 nM)。LY294002 可以激活凋亡和自噬。 | |||
T78097 |
Mazdutide
IBI-362,LY-3305677,OXM-3 |
||
Mazdutide (IBI-362; LY-3305677) 是一种具有安全性和耐受性的胃泌酸调节素类似物,用于肥胖和2型糖尿病(T2D)的研究。它同时作为胰高血糖素样肽(GLP-1R)和胰高血糖素受体(GCGR)的共激动剂,表现出长效作用。 | |||
T10379 |
Arzoxifene hydrochloride
SERM 3,LY 353381 HCl |
Others | Others |
Arzoxifene hydrochloride is a selective estrogen receptor modulator that is a potent estrogen antagonist in mammary and uterine tissue. | |||
T63150 | LY-411575 (isomer 3) | ||
LY-411575 isomer 3 是 LY411575 的异构体。其中 LY411575 是一种高效的 γ-secretase 抑制剂。 | |||
T80079 |
Mazdutide TFA
LY-3305677 TFA,IBI-362 TFA,OXM-3 TFA |
||
Mazdutide (IBI-362; LY-3305677) TFA 是一款GLP-1R与GCGR的共激动剂,同时是长效合成胃泌酸调节素类似物。该化合物安全性和耐受性良好,适用于肥胖与T2D研究。 | |||
T6018 |
Zosuquidar trihydrochloride
唑喹达三盐酸盐,Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride |
P-gp | Membrane transporter/Ion channel; Neuroscience |
Zosuquidar trihydrochloride (LY-335979 trihydrochloride) 是一种P-糖蛋白抑制剂,Ki 值为 59 nM。 | |||
T29421 |
LY195448
4-(3-(2-Hydroxy-2-phenyl)ethylamino-3-methylbutyl)benzamide |
Others | Others |
LY 195448 (4-(3-(2-Hydroxy-2-phenyl)ethylamino-3-methylbutyl)benzamide) 是存在于人血液和尿液中的一种物质,在小鼠肿瘤模型中显示出抗肿瘤活性,可在中期阻断细胞。 | |||
T16977 |
Talampanel
GYKI-53773,LY-300164 |
Apoptosis; GluR | Apoptosis; Neuroscience |
Talampanel (LY-300164) 是一种口服和选择型 AMPA 受体拮抗剂,具有抗癫痫活性。在啮齿动物的中风模型中,它 具有神经保护作用。Talampanel 减弱 caspase-3 依赖性细胞凋亡。 | |||
T1242 |
Alvimopan
爱维莫潘 |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Alvimopan (LY 246736) 是一种选择性和竞争性 μ 阿片受体拮抗剂,IC50值为 1.7 nM。它存在于肌间和黏膜下神经元以及人体肠道固有层的免疫细胞中,可用于术后肠梗阻的研究。 | |||
T0869 |
Atomoxetine hydrochloride
Tomoxetine hydrochloride,(R)-Tomoxetine hydrochloride,盐酸托莫西汀,LY 139603,Atomoxetine HCl,LY 139603 HCl |
Dopamine Receptor; 5-HT Receptor; Norepinephrine | GPCR/G Protein; Neuroscience |
Atomoxetine hydrochloride (LY 139603) 是苯氧基-3-丙胺衍生物和选择性非兴奋剂,是去甲肾上腺素再摄取抑制剂,具有认知增强活性。 与人 NET,SERT 和 DAT 的放射性配体结合的 Ki 分别为5,77和1451 nM。 | |||
T76950 | Zansecimab | ||
Zansecimab (LY-3127804) 为免疫球蛋白 G4-kappa 类型的血管生成素 2 (Ang 2) 单克隆抗体,具备于血管生成和免疫调节中的潜在应用。 | |||
T36349 |
CGP 74514 dihydrochloride
|
||
Potent cdk1 inhibitor (IC50 = 25 nM). Reduces Akt phosphorylation and increases mitochondrial damage in leukemia cells in vitro in combination with LY 294002. Yu et al (2013) The lethal effects of pharmacological cyclin-dependent kinase inhibitors in human leukemia cells proceed through a phosphatidylinositol 3-kinase/Akt-dependent process. Cancer Res. 63 1822 PMID:12702569 |Furet et al (2000) Structure-based design of potent CDK1 inhibitors derived from olomoucine. J.Comput.Aided Mol.Des. 14 40... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02358 |
CD98 Protein, Mouse, Recombinant (His)
NACAE,AI314110,Ly-m10,Cd98,Mgp-2hc,4F2HC,<... |
Mouse | HEK293 Cells |
CD98 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P10852-2. | |||
TMPY-04925 |
CD8 beta Protein, Human, Recombinant, Biotinylated
LY3,LYT3,CD8b molecule,P... |
Human | HEK293 Cells |
CD8 beta Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 17.6 kDa and the accession number is P10966-1. | |||
TMPY-00800 |
CD32B/Fcgr2b Protein, Mouse, Recombinant (His)
Fc fragment of IgG, low affinity IIb, receptor (CD3... |
Mouse | HEK293 Cells |
CD32B/Fcgr2b Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.7 kDa and the accession number is A0A0B4J1E6. | |||
TMPY-01145 |
NKp30/NCR3 Protein, Human, Recombinant (His)
NCR3,natural cytotoxicity triggering receptor 3... |
Human | HEK293 Cells |
NKp30/NCR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.4 kDa and the accession number is O14931-1. | |||
TMPJ-01154 |
SLAMF3 Protein, Mouse, Recombinant (His)
SLAM family member 3,T-lymphocyte... |
Mouse | HEK293 Cells |
CD229(SLAMF3) is a type I transmembrane glycoprotein in the SLAM subgroup of the CD2 family. Mature mouse CD229 consists of a 406 aa extracellular domain (ECD) with two Ig-like V-set and two Ig-like truncated C2-set domains, a 21 aa transmembrane segment, and a 180 aa cytoplasmic domain with two immunoreceptor tyrosinebased switch motifs ITSMs. Within the first two Ig-like domains that are common to all SLAM proteins, mouse CD229 shares 22%-36% aa sequence identity with mouse 2B4, BLAME, CD2F10,... | |||
TMPJ-00359 |
SLAMF3 Protein, Human, Recombinant (His)
Signaling lymphocytic activation molecule 3 |
Human | HEK293 Cells |
SLAMF3 (CD229) is a type I transmembrane glycoprotein in the SLAM subgroup of the CD2 family. Mature human SLAMF3 consists of a 407 amino acid (aa) extracellular domain (ECD) with two Ig-like V-set and two Ig-like truncated C2-set domains. The ECD of human SLAMF3 shares 57% - 59% aa sequence identity with mouse and rat SLAMF3. Within the first two Ig-like domains that are common to all SLAM proteins, human SLAMF3 shares 24% - 39% aa sequence identity with human 2B4, BLAME, CD2F-10, CD84, CRACC, ... | |||
TMPK-00091 |
NKp30/NCR3 Protein, Human, Recombinant (His & Avi), Biotinylated
1C7,LY117,CD337,NKp30,MA... |
Human | HEK293 Cells |
NKp30, along with NKp44 and NKp46, constitute a group of receptors termed "Natural Cytotoxicity Receptors". These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. | |||
TMPK-00090 |
NKp30/NCR3 Protein, Human, Recombinant (His & Avi)
NKp30,1C7,MALS,CD337,LY1... |
Human | HEK293 Cells |
NKp30, along with NKp44 and NKp46, constitute a group of receptors termed "Natural Cytotoxicity Receptors". These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature ph... | |||
TMPY-02703 |
CD8 beta Protein, Human, Recombinant (hFc)
LYT3,CD8 β,CD8b molecule,LY3<... |
Human | HEK293 Cells |
CD8 beta Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44 kDa and the accession number is P10966-1. | |||
TMPY-02925 |
CD8 beta Protein, Human, Recombinant
LEU2,P37,CD8b molecule,LYT3,CD8B1... |
Human | HEK293 Cells |
CD8 beta Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 17.6 kDa and the accession number is P10966-1. | |||
TMPY-05383 |
NKp30/NCR3 Protein, Human, Recombinant (hFc)
DAAP-90L16.3,natural cytotoxicity triggering recept... |
Human | HEK293 Cells |
NKp30/NCR3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is O14931-3. | |||
TMPY-01804 |
CD229 Protein, Mouse, Recombinant (His)
T100,SLAMF3,CD229,AI893573,Lgp100... |
Mouse | HEK293 Cells |
CD229 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.5 kDa and the accession number is Q01965. | |||
TMPY-01986 |
CD32B/Fcgr2b Protein, Mouse, Recombinant (His & Avi), Biotinylated
Fcgr2a,Fc fragment of IgG, low affinity IIb, receptor (CD |
Mouse | HEK293 Cells |
CD32B/Fcgr2b Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.9 kDa and the accession number is A0A0B4J1E6. | |||
TMPK-00358 |
CD229 Protein, Human, Recombinant (His & Avi), Biotinylated
T100,Lgp100,LY9,AI893573,CD229,SL... |
Human | HEK293 Cells |
CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells. CD229 Protein, Human, Recombinant (His & Avi), B... | |||
TMPK-00357 |
CD229 Protein, Human, Recombinant (His & Avi)
LY9,T100,AI893573,SLAMF3... |
Human | HEK293 Cells |
CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells. CD229 Protein, Human, Recombinant (His & Avi) is... | |||
TMPY-02793 |
CD40 Ligand Protein, Mouse, Recombinant (hFc)
gp39,CD40 ligand,IGM,Cd40l,CD40-L,T-BAM,TRAP,CD154,... |
Mouse | HEK293 Cells |
CD40 Ligand Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.4 kDa and the accession number is P27548. | |||
TMPY-06687 |
CD40 Ligand Protein, Mouse, Recombinant (His)
IGM,IMD3,TRAP,Ly62,CD40-L,Tnfsf5,CD154,T-B... |
Mouse | HEK293 Cells |
CD40 Ligand Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.37 kDa and the accession number is P27548. | |||
TMPJ-00083 |
NCR3 Protein, Human, Recombinant (hFc)
Activating Natural Killer Receptor p30,CD3... |
Human | HEK293 Cells |
Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed “Natural Cytotoxicity Receptors”. They play a major role in triggering NK-mediated killing of most tumor cells lines. NKp30 is a type I transmembrane protein having a single extracellular V-like immunoglobulin domain. NKp30 is selectively expressed both in resting and activated human NK cells. In addition, NKp30 is also involved in NK-mediated induction of dendritic cell (DC) matur... | |||
TMPY-06986 |
FGF-8b Protein, Human, Recombinant
NEWENTRY,fibroblast growth factor 8 (androgen-induced),FGF-8... |
Human | E. coli |
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac... | |||
TMPY-00132 |
Mesothelin Protein, Human, Recombinant
MPF,SMRP,Mesothelin |
Human | HEK293 Cells |
Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3. | |||
TMPY-04935 |
CD47 Protein, Human, Recombinant (aa 1-139, His)
MER6,CD47 molecule,IAP,OA3 |
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q08722-3. | |||
TMPY-03763 |
Neuropilin-2 Protein, Human, Recombinant (hFc)
Neuropilin-2,NPN2,neuropilin 2,PRO2714,VEGF165R2,NP2 |
Human | HEK293 Cells |
Neuropilin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 120.7 kDa and the accession number is O60462-3. | |||
TMPY-05191 |
CD47 Protein, Human, Recombinant, Biotinylated
CD47 molecule,MER6,OA3,IAP |
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3. | |||
TMPY-04683 |
CD47 Protein, Human, Recombinant
MER6,CD47 molecule,OA3,IAP |
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3. | |||
TMPY-00072 |
GITR/TNFRSF18 Protein, Human, Recombinant (His)
AITR,GITR-D,tumor necrosis factor receptor superfamily |
Human | HEK293 Cells |
GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3. | |||
TMPY-01020 |
Periostin/OSF-2 Protein, Human, Recombinant (His)
PN,OSF-2,OSF2,periostin,periostin, osteoblast specific facto... |
Human | HEK293 Cells |
Periostin/OSF-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is Q15063-3. | |||
TMPY-00892 |
Neuropilin-2 Protein, Human, Recombinant (His)
NP2,PRO2714,VEGF165R2,neuropilin 2,NPN2,Neuropilin-2 |
Human | HEK293 Cells |
Neuropilin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is O60462-3. | |||
TMPY-01897 |
PRSS3 Protein, Human, Recombinant (His)
PRSS4,TRY4,TRY3,RP11-176F3.3,T9,M... |
Human | HEK293 Cells |
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ... | |||
TMPY-05748 |
CD45 Protein, Human, Recombinant (aa 26-577, His)
L-CA,T200,LCA,B220,protein tyrosine phosphatase, receptor ty... |
Human | HEK293 Cells |
CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3. | |||
TMPY-04142 |
RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
OPTB7,OFE,OSTS,LOH18CR1,FEO,TRANCER,tumor necrosis factor re... |
Human | HEK293 Cells |
RANK/TNFRSF11A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9Y6Q6-3. | |||
TMPJ-01099 |
IL-15RA Protein, Human, Recombinant (hFc, Human Cells)
interleukin-15 receptor subunit α,IL15RA,interleukin-15 rece... |
Human | HEK293 Cells |
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-boun... | |||
TMPY-01180 |
CD86 Protein, Human, Recombinant (His)
CD86 antigen,B70,B7.2,B7-2,CD28LG2,LAB72 |
Human | HEK293 Cells |
CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3. | |||
TMPY-04298 |
CDCP1 Protein, Human, Recombinant (His)
TRASK,CD318,CUB domain containing protein 1,SIMA1 |
Human | HEK293 Cells |
CDCP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q9H5V8-3. | |||
TMPY-00357 |
HNT/NTM Protein, Human, Recombinant (His)
HNT,NTRI,IGLON2,neurotrimin |
Human | HEK293 Cells |
HNT/NTM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q9P121-3. | |||
TMPY-00480 |
NCAM1 Protein, Human, Recombinant (His)
neural cell adhesion molecule 1,CD56,MSK39,NCAM |
Human | HEK293 Cells |
NCAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.1 kDa and the accession number is P13591-3. | |||
TMPK-00447 |
CD45 Protein, Human, Recombinant (aa 26-577, hFc)
CD45,CD45R,LCA,PTPRC,L-CA,T200,B220,GP180,LY5,EC |
Human | HEK293 Cells |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (aa 26-577... | |||
TMPY-03621 |
EphB2 Protein, Mouse, Recombinant (hFc)
Tyro5,Erk,Qek5,ETECK,Hek5,Drt,EPH receptor B2,Nuk,Prkm5,Sek<... |
Mouse | HEK293 Cells |
EphB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.6 kDa and the accession number is P54763-3. | |||
TMPJ-01288 |
KLF6 Protein, Human, Recombinant
CPBP,GC-Rich Sites-Binding Factor GBF,Suppressor of Tumorige... |
Human | E. coli |
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will resul... | |||
TMPY-04386 |
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)
PCBC,CAPB,Hek5,EK5,EPHT3,EPH receptor B2,Tyro5,DRT,... |
Human | Baculovirus Insect Cells |
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.2 kDa and the accession number is P29323-3. | |||
TMPY-01268 |
SMYD3 Protein, Human, Recombinant (GST)
SET and MYND domain containing 3,ZMYND1,KMT3 |
Human | Baculovirus Insect Cells |
SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger and one SET domain. SMYD3 is a histone H3 lysine-4-specific methyltransferase. It is expressed in skeletal muscles and testis. It is overexpressed in a majority of colorectal carcinoma (CRC) and hepatocellular carcinoma (HCC). SMYD3 plays an important role in transcriptional reg... | |||
TMPY-03149 |
CDCP1 Protein, Human, Recombinant (mFc)
TRASK,SIMA135,CD318,CUB domain containing ... |
Human | HEK293 Cells |
CDCP1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 61.4 kDa and the accession number is Q9H5V8-3. | |||
TMPK-00401 |
FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
ECT1,K-SAM,CD332,CEK3,FGFR2 α,CFD... |
Human | HEK293 Cells |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. | |||
TMPK-00398 |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
Fibroblast growth factor receptor 2,CD332,... |
Human | HEK293 Cells |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3. | |||
TMPJ-00391 |
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
FGF R2b,KGFR,BFR-1,FGFR2 β,FGFR2b,FGFR2,FGFR2 beta,CD3 |
Human | HEK293 Cells |
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802-3. | |||
TMPY-05514 |
RANK/TNFRSF11A Protein, Human, Recombinant (mFc)
OFE,RANK,OPTB7,FEO,tumor necrosis factor receptor superfami<... |
Human | HEK293 Cells |
RANK/TNFRSF11A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q9Y6Q6-3. | |||
TMPY-00276 |
PLGF/PGF Protein, Human, Recombinant (mFc)
placental growth factor,D12S1900,PLGF,SHGC-10760,PGFL,PlGF-2 |
Human | HEK293 Cells |
PLGF/PGF Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.7 kDa and the accession number is P49763-3. | |||
TMPY-03960 |
COL9A1 Protein, Human, Recombinant (His)
EDM6,collagen, type IX, α1,STL4,collagen, type IX, alpha 1,M... |
Human | HEK293 Cells |
COL9A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.2 kDa and the accession number is P20849-3. | |||
TMPY-04015 |
COL9A1 Protein, Human, Recombinant (mFc)
DJ149L1.1.2,STL4,collagen, type IX, alpha 1,MED,EDM6,collage... |
Human | HEK293 Cells |
COL9A1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 59.2 kDa and the accession number is P20849-3. | |||
TMPY-06411 |
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated
CD357,GITR-D,tumor necrosis factor receptor superfa... |
Human | HEK293 Cells |
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.79 kDa and the accession number is Q9Y5U5-3. | |||
TMPY-00715 |
CD84 Protein, Human, Recombinant (His)
LY9B,mCD84,CD84 molecule,hCD84,SLAMF5 |
Human | HEK293 Cells |
CD84 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9UIB8-3. | |||
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